ABSTRACT
This chapter discusses other types of toxic effects that have been observed in humans as well as in experimentally exposed animals. Similar hypertensive responses were observed in all exposure groups, indicating that the hypertensive effect of cadmium is relevant not only for one strain or sex of rats. After high peroral, parenteral, or inhalative exposure to most cadmium compounds, high concentrations of the metal will be found in liver. Data on long-term effects of cadmium on the gastrointestinal tract are scarce. When cadmium is administered parenterally, high doses are necessary in order to produce any effect at all on the hematopoietic system. Exposure to high doses of cadmium via inhalation, perorally or parenterally, can give rise to morphologic changes in the liver. Single or a small number of parenteral administrations of cadmium salts to animals can give rise to either a decrease or an increase in blood pressure.
