ABSTRACT

Red Blood Cells (RBCs) have a high deformability capability that allows them to reach all parts of the body. In certain pathologies this capacity is affected. The high rates of new diagnoses of these diseases have attracted the interest of the scientific community, which has performed a significant amount of research in this area. In this article, a two-dimensional simulation was performed using healthy and pathological red cells (ovalocytosis and sickle cell anemia). The aim, of this article, is to understand the behaviour of healthy and pathological cells when subjected to a force and a boundary condition. In the simulation, it was applied the Finite Element Method (FEM) and two meshless methods: The Radial Point Interpolation Method (RPIM) and the Natural Neighbour Radial Point Interpolation Method (NNRPIM).