ABSTRACT
The liver can be implanted either orthotopically or heterotopically. A heterotopic nonauxiliary transplantation hardly seems reasonable, and at most, may be justifiable in animal experiments. The operations were conducted under ether inhalation anesthesia and mostly with sterilized instruments, even though using only cleansed instruments would be totally sufficient for rats. The results of the heterotopic auxiliary transplantation in our thioacetamide cirrhosis model, i.e., in chronic liver damage, were disappointing. The method section provides a description of animal material, the thioacetamide cirrhosis model, and the operation technique. Biochemical studies and oxygen pressure measurements are mentioned as well. The graft liver, which had been resected to about 30% hypertrophied at first compensationally, later achieving true regeneration. The local oxygen pressure at first measured the same as a normal liver supplied both portally and arterially. On account of the poor survival rates, the heterotopic auxiliary liver transplantation was not successful in cirrhotic rats.
