ABSTRACT
This chapter analyses the literature available on the effects of hyperthermia on capillary flow and morphology. Proximal to the capillary network, vessels of near–capillary dimension showing occasionally vasomotor activity prior to the implantation of tumor cells were defines as precapillaries. The melanoma is maintained by biweekly passage in inbred Syrian hamsters and harvested by sterile excision. An accurate temperature reading in the tissue preparation and the tumor simultaneously with microhemodynamic data, removal of the cover glass is necessary. The terminal vascular bed of malignant tumors consists of capillaries that originated from venous segments of the microcirculation. The dissipation of heat in malignancies is strongly related to the capacity of the circulatory system to furnish the tumor with a sufficient amount of blood. The quantitative data on hemodynamic changes in the microcirculation after local hyperthermia. The measuring microhemodynamic parameters at the level of “single vessels” offers the opportunity.
