ABSTRACT
The modern history of anti-phospholipid antibodies (aPL) possibly started in 1906 with Wassermann’s reagin test. For me, involvement in aPL began somewhat fortuitously in 1973, when, as a speaker in the Royal College of Physicians advanced medicine course, I was accompanied by Dr. R. D. Catterall who presented his lifetime’s experience of a follow-up of individuals with false-positive serological tests for syphilis.1 There were, he reported, a small group of patients with false-positive STS who developed an “atypical” multiple sclerosis—“lupoid sclerosis.”
