ABSTRACT
This chapter focuses on the different synthetic polymer-based nanosystems and the pharmaceutical applications in drug delivery. Poly(acrylic acid) is a highly water-soluble and biodegradable synthetic polymer that can be prepared by free-radical polymerization with broad molecular weight distribution. Polyoxazoline has been used in other applications such as in preparations of nanoscale systems, thermo responsive systems, gene delivery, and deoxyribonucleic acid and ribonucleic acid delivery into cells. Poly(vinyl pyrrolidone) is used in medicine as a surface modification agent. Polyacrylamide is a water-soluble polymer with a wide range of uses, including oil recovery, cosmetics, and biomedical applications such as carriers for delivery of drugs and bioactive molecules. Polyoxazolines are structurally similar to peptides, making them interesting in the biomedical field. Polyphosphazenes, known as hybrid inorganic-organic polymers, are a relatively new class of polymers and are notably distinct from all other biodegradable polymers because of their synthetic flexibility and versatile adaptability for applications.
