This chapter traces human interest in the ocean sunfishes, Molidae, and their multifaceted uses: from being ichthyological oddities noted by the ancient Greeks, to being culinary delicacies, medical cures, aphrodisiacs, public engagement superstars, a muse for artists and video gamers, and a bucket list item for ecotourists. Since the first description of the family Molidae, more than five centuries ago, interest in molids has steadily risen. Alongside a growing understanding of connectivity and resilience within marine systems, these remarkable fish may be most impactful as engaging ambassadors inspiring humanity to care more deeply about the future of the ocean and strive to better safeguard its declining health.