ABSTRACT
Dupuytren's contracture (DC) is an autosomal dominant (AD) disorder characterized by the development of a chronic fibrotic palmar contracture that progressively draws the digits into the palm. Skin, subcutaneous tissue and the palmar aponeurosis cover the tendon sheaths, the tendons and the bones of the hand. The palmar aponeurosis tethers the bones together, maintains the shape of the palm and prevents the tendons from bow-stringing across the palm when the hand is cupped. Alcohol consumption is a predisposing factor. Psoriasis is a skin disease widely recognized for its systemic pathogenic effects, so much so that it is now considered as much a systemic as a cutaneous disease. The usual natural history of DC is one of ratchet-like progression rather than steady worsening. DC is a common, progressive and disabling disease, chiefly of older white men. DC patients require a physicianly and holistic approach as DC is associated with many other important disorders.
