ABSTRACT

Cell-based therapy is one of the regenerative medicine branches that consists of using living cells as biological medicine for therapeutic purposes. Nanotechnology is a multidisciplinary field that provides a suitable situation for medical researchers to manipulate biomaterials, tissues, cells, drugs and nucleic acids for use in different medical applications. Nanomaterials that regulate cell adhesion, proliferation and differentiation can be used for targeting transplanted cells’ migration and delivery to localized target injured sites. Cellular membranes are a good pattern for cell delivery systems (CDS) that these biomimetic CDSs whose morphology, surface properties and size imitate natural tissue possess special functions to enhance delivery and cell homing in target tissues. Porous biomaterials have been widely used as scaffolds in cell-based therapies of several diseases. With great progress being made in the synthesis of nanostructures, there are interesting new opportunities for regenerative medicine, in particular, cell therapy and CDSs.