ABSTRACT
Melanoma is one of the most aggressive types of skin cancer, having a low survival rate, easy to relapse, and a notorious high multidrug resistance. In this chapter, we intend to elucidate the possibility to treat melanoma skin cancer using the development of nanofibers by advanced electrospinning process. We present a brief introduction of the pathogenesis of melanoma, a concise compilation electrospun mats, and their application in the biomedical field. The composite electrospun mats work as drug delivery system, which can be made by the combination of different polymers, with anticancer activity for melanoma skin.
The chapter also gives an overview of an auspicious manufacturing method of fabricating of biocompatible tissue engineering scaffolds, by designing efficient drug formulations with an effective approach and rapid prototyping, featuring the ability of producing predetermined structures and forms with very high level of repeatability and accuracy. The advantages of 3D printing of tissue engineering scaffolds are presented. By tuning the pore network structure in 3D scaffolds, it is possible to achieve sustained nutrients, homogenous cell distribution, and oxygen accessibility.
