ABSTRACT
Allergic bronchopulmonary aspergillosis (ABPA) is a lung disease caused by an immunologic response to the mold Aspergillus fumigatus. The disease is mostly described in genetically susceptible asthmatics and cystic fibrosis (CF) patients. An exaggerated host immune response involving Th2 CD4+T cells is central to the pathogenesis of ABPA. The diagnosis of ABPA requires the combination of clinical, radiographic, and laboratory criteria.
This chapter reviews the major pathologic manifestations of ABPA, clinical, radiographic, and laboratory features of the disease and current knowledge about its pathogenesis and treatment.
