ABSTRACT

The definition and theoretical fundamentals of a new scientific trend—physical–chemical pharmacology are considered on the example of the mechanical, physical, chemical, and physical–chemical properties of modern pharmaceutical tablets. The theoretical, laboratorical, and experimental methods for the processes prognosis action of medications as well as for the local physical–chemical systems reactivity estimation are discussed. It is shown that modern tablets are significantly different from natural food clumps, which people swallow after chewing of bread. The fact is that today tablets are prepared by pressing, and therefore represent artificial stones. Proposed to change, the technology of production of 264tablets to tablet is fully consistent with artificial food lumps. The basic mechanical, physical, chemical, and physical–chemical parameters of natural food clumps are determined. The harmful effects influence of sizes, shapes, hardness values, solubility, osmotic, and acid activity tablets on the healthy and diseased teeth, different dental constructions, and on mucous membranes of the mouth and stomach is shown. It is shown that the danger of modern tablets for people due to their “wrong” mechanical, physical, chemical, and physical–chemical properties. It is shown that for the acquisition of high security, pharmaceutical tablets must be in the form of olive fruit, being soft and porous like chewed bread, and not be sinking like stones, but to be floating, like the foam.