The goal of this summary chapter is twofold. The first is to provide the reader an overview of the content of the preceding chapters. This they can read at the very beginning, before moving on to individual chapters in detail. Alternatively, they may read it at the very end to refresh their memory and to summarize the contents of the Volume. Second, this summary provides the editors’ perspective, bringing in their rich collective experience and expertise to guide the reader. We have kept the summaries brief and illustrative, so that the reader can quickly gather essential initial knowledge and guidance. The in-depth details can be found in the individual chapters.