ABSTRACT
Hybrid imaging with PET/CT or SPECT/CT systems is performed for a variety of tasks from diagnosis to treatment monitoring over a wide range of clinical applications including oncology, neurology, cardiology, and musculoskeletal imaging. With these systems, the patient is exposed to ionizing radiation from both the administered radiopharmaceutical and the CT component. This work describes the radiation dosimetry aspects of PET/CT and SPECT/CT systems in an effort to inform appropriate protocol design. In general, acquisition protocols should be task-, application-, and patient-specific in order to generate clinical information with sufficient performance at a minimal level of risk.
