ABSTRACT

Gas chromatography coupled with mass spectrometry (GC-MS) and gas chromatography coupled with tandem mass spectrometry (GC-MS/MS) techniques seem to be powerful tools in modern bioanalytic studies relating to the identification and quantification of environmental bioindicator residues in food, environmental, and biological samples. Gas chromatographic multiresidue analysis of xenobiotic residues in food represents a challenging analytical problem, since multiple target analytes have to be determined within one run in samples containing large amounts of co-extracted matrix components. The GC-MS is increasingly becoming a primary tool for the determination of environmental bioindicator residues in food. Bioindicators provide specialized information to the general population and/or professionals for acquiring an accurate perception of specific issues on the status of society or on personal actions. Analytical strategies for determining mycotoxins have been divided into two categories: reference methodologies for quantitative analysis and rapid methodologies for first-level screening of numerous samples.