ABSTRACT
In recurrent pregnancy loss (RPL), when no underlying cause can be identified, empirical treatments are offered to couples with RPL, including assisted reproductive technique (ART). Although most patients with RPL do not have fertility problems, RPL patients are often offered a selection of adjunct treatments or “add-ons” aiming to improve their chance of a live birth. This chapter presents the clinical evidence and assess the benefit or lack of benefit of the various options offered in ART in RPL patients. In RPL, the live birth rate is quoted as the number of live births per pregnancy. In in vitro fertilizatio, the clinical pregnancy rate is often used as a measure of the success of treatment. In RPL, the clinical pregnancy rate is meaningless, as RPL patients generally conceive easily. The assessment and treatment of couples with RPL has been directed exclusively to investigation of the female rather than the male partner.
