Non-communicable disease and mental health disorders pose a substantial threat to global health. It is known that exercise has a crucial role in maintaining a healthy lifestyle and reducing the risk of developing various non-communicable medical conditions and/or mood disorders. The gut microbiota is also essential in the development of the immune system and can have a role in reducing the risk of developing diseases such as colon cancer and type II diabetes. Probiotic bacteria are known as the friendly bacteria within gastro-intestinal tract. It is widely recognised that probiotics can positively influence mood state due to the effect they can have on both anatomical connections such as the vagus nerve and humoral components such as the immune system and hypothalamus-pituitary-adrenal axis. The link between the gut microbiota and body fat has been demonstrated both in animal and human studies.