ABSTRACT

The blood-brain barrier (BBB) which maintains the neural homeostasis remains as a major hindrance for many medical imaging and drug penetration procedures in case of tumors or cancers. Through intensive research works, many routes have been found to penetrate the BBB using micelles, polymeric nanoparticles, and liposomes as drug carriers. One of the most focused and emerging fields is using gold nanoparticles (AuNPs). Its tunable optoelectronic properties, along with high photostability, multifunctionality, and biocompatibility, have given it an upper hand in comparison with other existing techniques. In this chapter, we are going to focus on synthesis of AuNPs and utilizing them for brain targeting using its multifunctional properties.