ABSTRACT

Pergularia daemia (Forssk.) Chiov. is commonly known as “Velipparuthi” and its leaves are traditionally used to treat fevers, rheumatism, liver disorders, emetic, and expectorant. The main objective of this study is to evaluate the anticancer effect of P. daemia against human cervical cancer cell lines (HeLa) and human embryonic kidney cell lines (HEK 293). The ethanol extract of the leaves showed significant dose dependent effects on both the cell lines. The IC50 value was found to be 6.6 μg/mL for HeLa and 33.07 μg/ mL for HEK cell lines. Hence this study has revealed remarkable anticancer potential in the leaves of P. daemia.