ABSTRACT
Cancer rates are tolling high constantly worldwide. High life expectancy, environmental changes, urbanization, and changing lifestyles have been vital contributive factors for the hike in carcinogenesis. Colorectal carcinoma (CRC) is the cancer that starts in distal alimentary canal involving colon and/or rectum. Most of the CRC initiate with the development of “polyps,” which are small growth on the inner lining of colon or rectum. Cancer is one of the diseases having a strong genetic basis that basically develops due to an imbalance of tumor suppressor gene and the oncogene DNA expressions. Several types of nutraceuticals have been identified to play a vital role in the inhibition of growth and spread of CRC. Many of the nutraceuticals in spite of having high anticancer potential in vitro fail to be successful in vivo due to their poor bioavailability.
