ABSTRACT

Fibromyalgia is a complex chronic health condition that causes widespread pain and tenderness and a heightened sensitivity to sounds, light, and touch. The pain varies in intensity, migrates around the body, and has been described as stabbing and shooting, with deep muscular aching, throbbing, and twitching. The causes of fibromyalgia are not clear and can vary among different people. Fibromyalgia is considered its own entity as it does not fit an autoimmune, inflammation, joint, or muscle disorder in the classic sense. Research suggests that the central nervous system in particular plays an active role in fibromyalgia pain. A variety of possible mechanisms have been proposed but, because these mechanistic abnormalities are found in all patients, finding effective treatments has been difficult. Dopamine is a neurotransmitter that has been shown to have analgesic effects within the central nervous system. Ambroxol is a secretolytic agent used in the treatment of diseases associated with viscid or excessive mucus.