ABSTRACT
Over the past 30 years, liposomes have been proposed as a vehicle for improving the delivery (and thereby the therapeutic utility) of dozens of drugs. The cytotoxic anthracycline antibiotics doxorubicin and daunorubicin and the polyene antibiotics amphotericin B and nystatin are perhaps the most often cited examples. The vast majority of these publications originated from academic laboratories and thus do not generally address the pharmaceutical attributes required for the regulatory approval of a commercially viable product.
