ABSTRACT

From a practical viewpoint, it remains difficult to draw valid conclusions from the literature concerning the absorption level of a given compound. This is essentially due to the diversity of techniques used, animal species (1,2), anatomical location (3,4), duration of application (1), dose applied (5,6), and vehicle used (1,7). Furthermore, because this kind of research has interested scientists from widely differing disciplines, each worker has chosen or adapted the methodology to elucidate a particular problem.