ABSTRACT
This therapy was first performed in Argentina (1) and later in France, in the thermal waters station of Royat, near Clermont Ferrand (2). There, a group of cardiologists from the hospital of Clermont Ferrand began to treat patients with peripheral organic and functional arteriopathies (atherosclerotic, Buerger’s disease, Raynaud’s disease, etc.). In 1953, the cardiologist Jean Baptiste Romuef published a paper about his 20 years of experience in using subcutaneous injections of CO2 for treatments (3). Later, the Parisian cardiologist Jerome Berthier, along with Luigi Parassoni from Gaillard A, started to apply it in patients with cellulite (4).
