ABSTRACT
The momentum produced by the sequencing of the human
genome has rapidly spilled over into the study of gene
transcripts, proteins, and small molecule metabolites.
The current trend in biology is no longer to study individ-
ual components, but to study the cell as a whole. This trend
has not only spawned several new technologies (i.e.,
cDNA and protein arrays), but also has brought about
the realization of unrecognized utilities possessed by
existing technologies (i.e., metabonomics analysis using
nuclear magnetic resonance spectroscopy). One of the
largest trends is the development of methods to analyze
large numbers of proteins in single experiments. These
so-called “proteomics” approaches provide a powerful
means to examine global changes in protein levels and
expression under changing environmental conditions.
