ABSTRACT

Meeting Industry and Market Needs Industry and market needs have increasingly dictated the course of oral solid dosage manufacturing. Historically, solid dosage products date back to the seventeenth century in the United States. Until the 1920s, 80 % of the medicines that were compounded were produced by pharmacists in liquid, powder, and tablet form. Due to the healthcare needs of World War I’s military, higher technology medicines were required to treat the injured and to cure diseases that became major health issues. The production of tablets, based on newly created drugs, became a prominent industry in the United States. Now, common definition of “solid dosage products” includes tablets, hard shell and soft gelatin capsules, and a variety of novel forms of drug delivery. These novel forms include quick dissolve, effervescent, and powdered products.