ABSTRACT
INTRODUCTION Containment has increased in importance in the pharmaceutical industry over the last decade. The reasons for this are not hard to find. Active pharmaceutical ingredients (API) have increased in activity dramatically as more targeted drug delivery systems have emerged. Pharmaceutical companies’ pipelines have moved from a position where potent entities were a minority, to the current position where they are the majority. Some companies now have 80% of their pipelines as potent, and this trend shows no signs of diminishing.
