ABSTRACT

Because of lifelong exposure to immunosuppressive medication, organ transplant recipients are at markedly increased risk for skin cancer; apart from keratinocyte cancer, they have also a high burden of various skin diseases compared with that of the general population, with skin infections either of fungal, viral, or bacterial origin most commonly becoming manifest. Among the conditions leading to skin symptoms due to infectious pathogens are an alteration of the skin barrier, the degree and type of immunosuppression, and the presence of septicemia with possible metastatic spread to the skin. The skin may also be the site of infections with opportunistic pathogens generally without pathogenic potency for humans, which is the domain of a large spectrum of fungi.