Technological advances in imaging modalities are greatly expanding in the dermatologic field with many implications for surveillance, diagnosis, management, and treatment of skin cancer in organ transplant patients. Utilization of modalities such as total body photography, dermoscopy, reflectance confocal microscopy, optical coherence tomography, and ultrasound increases the likelihood of identifying suspicious lesions, aids proper diagnosis of malignant lesions, guides decisions about treatment modalities, and improves posttreatment surveillance. The development of applications using artificial intelligence can aid clinicians, and it is expanding from use with clinical photographs to other methods of noninvasive imaging. Guidelines as to how to best use noninvasive imaging in the management of skin cancer in organ transplant patients have not yet been delineated but recommendations can be put forth based on other high-risk patient populations.