ABSTRACT
The problem in eliminating a chronic infection associated with biofilm production lies in fact that biofilm bacteria by virtue of reduced permeability and dormant persistence are able to survive greater antibiotic concentration. With the objective of identifying naturally formed biofilm producers, inhibiting further colonization of other biofilm producers on them, a strong biofilm producing Aeromonas sobria was isolated from slimy layer of Indian cat fish, confirmed by vitek-2 automated system. Biofilm formation of Aeromonas over cut silicon catheter chips and on 96 well microtitre plates was quantified by OD values followed by subsequent growth of a known biofilm positive Staphylococcus aureus (methicillin resistant) over the Aeromonas biofilm catheter chips was assessed. The results showed inhibition of growth of Staphylococcus in the background of Aeromonas both under microscopy and significant difference in OD values from 0.347892 to 0.03521
