ABSTRACT

In 1947, a group of researchers found that fever developed in a caged rhesus macaque in the Zika forest, near the East African Virus Research Institute in Entebbe, Uganda. The researchers isolated from the serum of the monkey a transmissible agent that was first described as Zika virus (ZIKV) in 1952. In January 2016, the CDC issued a level 2 alert for people traveling to regions where ZIKV transmission was ongoing. The agency also advised that pregnant women should consult with doctor before traveling. Information regarding the countries and areas with active ZIKV transmission has been availed. Moreover, the Pan America Health Organization had alarmed Brazil about the ZIKV infection in May 2015. ZIKV is an insect-borne virus, belonging to the Flavivirus genus in the Flaviviridae family, which causes fever. It is somewhat similar to dengue, yellow fever, West Nile fever, Japanese encephalitis, and viruses that are members of the family Flaviviridae.