ABSTRACT
Yellow fever (YF) is a mosquito-borne flaviviral hemorrhagic fever. This fever may cause hepatitis, kidney malfunctioning, hemorrhage, and multiorgan failure. Attack of yellow fever virus (YFV) has caused several outbreaks in the world. Conventionally, YFV is detected by using clinical approaches, but better results could not be obtained. YF is an acute viral hemorrhagic disease. It is transmitted from infected mosquitoes. The word “yellow” refers to the jaundice that affects some patients. In the past, YF was reported in countries such as Africa, the Americas, Europe, and the Caribbean. The RNA is positive-sense, single-stranded RNA and contains 11,000 nucleotides with a single open reading frame encoding a polyprotein. YF is caused by prototype YFV that belongs to the genus Flavivirus and the family Flaviviridae. Symptoms of YFV infection may vary from mild to hemorrhagic, which leads to failure of vital organs.
