ABSTRACT

Network Biology and Network Medicine have been established as legitimate research and applied scientific disciplines in recent times. With the growth of Network Science from the tenets of graph theory, powerful analytical and computational methods have been developed that, within the network paradigm, have proven to be quite useful to study and characterize a broad range of biological phenomena. In this chapter, the general ideas of network theory as applied to biological networks, reviewed a number of applications within the biological/biomedical setting are introduced. After that, biological network analytics are characterized and some of the most widely used theoretical approaches and computational methods to perform analysis of biological networks are presented. Finally, some of the more useful/reliable bioinformatic tools to perform such analyses are discussed.