ABSTRACT
Psoriasis is a chronic and immune-mediated inflammatory skin disease. Genital psoriasis occurs in 30-60% of patients with plaque psoriasis and in up to 80% of patients with inverse psoriasis during the course of the disease. Psoriasis of the genitalia often appears as well-demarcated, brightly erythematous, thin plaques. In infants, genital psoriasis appears as well-demarcated, erythematous, and sometimes silvery plaques in the diaper area, termed napkin psoriasis. Genital psoriasis goes largely undiagnosed, especially in those cases exclusively localized in this area, even though it has a detrimental impact on quality of life and sexual health. The diagnosis is usually clinical, especially when genital lesions are part of a more generalized form of psoriasis. Dermoscopy and reflectance confocal microscopy, the latter showing dark dermal papillae filled with dilated and round vessels, are very useful to support the diagnosis, although histopathological examination is sometimes required. The dermoscopic pattern of psoriasis has been extensively described in the literature.
