ABSTRACT
Genital warts (GWs), also known as condylomata acuminata, represent a common, highly contagious transmissible infection of the genital and perigenital areas, more often observed in young and sexually active individuals, that are caused by human papillomavirus (HPV). GWs represent one of the most frequent sexually transmissible diseases, with a worldwide prevalence rate variable from 2% to 44%. LR-HPV types 6 and 11 are responsible for more than 90% of the GWs. The main differential diagnoses of GWs include molluscum contagiosum, pearly penile papules or vestibular papillomatosis, Fordyce's spots, angiokeratoma, lymphangioma, lichen nitidus and epidermoid cyst. The diagnosis of GWs is usually simple and based on the typical clinical appearance. Histopathological examination may sometimes be necessary when dermoscopy is also doubtful. Dermoscopy of GWs, extensively described in both sexes, varies depending on the clinical presentation. Histopathologically, GWs are characterized by a compact stratum corneum, acanthosis and different degree of papillomatosis with increased vascularization.
