ABSTRACT
Botulinum toxin is indicated in aesthetic medicine mostly for mimetic muscle modulation (wrinkles and contours), muscle tone adjustment (refreshing and relaxing) and bulge reduction (contours), muscle rebalancing (facial landmark reposition and lifting), releasing tissue spaces, and smoothing the skin surface. The toxin is also used in superficial skin for skin quality enhancement and in vessels and skin appendages for function modulation. Botulinum toxin in practice is combined less often with chemical peels, but intradermal toxin injection has been reported to help to control acne and seborrhea, and also to enhance radiance and achieve a smoother texture. Those are also the goals of chemical peeling treatment. Facial shapes could be enhanced by volume augmentation through filler injection; part of the facial shape could be adjusted by the modulation of muscles with botulinum toxin. Fillers and toxin work synergistically like sculpting, aiming toward both volume reduction and augmentation.
