ABSTRACT
For a subject's friends and acquaintances who detect the differences, the awareness can be attributed to the comparison of the original muscle exercising pattern they are used to and the new one that presents after the toxin treatment. Facial muscle synergism works in various patterns, as documented in the literature, but most of us can compile these patterns as normal. The goal of wrinkle treatment should be to ameliorate the magnitude or strength of muscle contraction, instead of completely eradicating it. The aim of an aesthetic treatment with toxin injection would be to administer doses moderately and respect the pattern of muscle synergism. Physical examination should include visual observation of muscle excursion and palpable evaluation of muscle strength. Synergism is a common phenomenon where a group of muscles is innervated in a parallel connection. The parallel innervation could be strongly associated or partially connected.
