ABSTRACT
Iodine is an essential dietary mineral used for the biosynthesis of tri-iodothyronine and thyroxine by the thyroid gland. Potassium iodide (KI) was first isolated in seaweed in the 19th century and thereafter used to treat thyroid disease and various dermatological and infectious diseases. KI has an immunomodulatory mode of action with specific effects on neutrophil function. KI has an immunomodulatory mode of action with specific effects on neutrophil function. Tablets have a bitter taste and should be swallowed whole with plenty of water. Aqueous solution of KI may be diluted with water, juice or milk and drunk with a straw to limit dental staining. Improved tolerance to gastrointestinal side effects is achieved by administering in 2—3 divided daily doses and by gradual dose increments over a few weeks to the treatment dose. Drugs that cause hyperkalaemia, including spironolactone, angiotensin-converting enzyme inhibitors, potassium sparing diuretics and ciclosporin.
