ABSTRACT
Liver disease is increasing worldwide. Most liver disease is preventable, but it is frequently identified too late. Hepatitis B and C virus infection remain highly prevalent globally and screening should be undertaken before starting drugs with immunosuppressant actions. It is not possible, on clinical grounds, to differentiate hepatitis B from hepatitis caused by other viral agents. Hence, laboratory confirmation of the diagnosis is essential. A number of blood tests are available to diagnose and monitor people with hepatitis B. They can be used to distinguish acute and chronic infections. Laboratory diagnosis of hepatitis B infection focuses on the detection of the hepatitis B surface antigen (HBsAg). Prescribing systemic dermatological treatment in patients with pre-existing liver disease can present challenges, as many of these drugs can cause liver damage.
