ABSTRACT
Glycyrrhiza is considered to possess ulcer-protective, demulcent, antitussive, expectorant, and laxative properties. The saponins and flavonoids are both considered to be the major bioactive constituents of licorice. Licorice in present days also continues to serve as a flavoring agent, sweetening the bitter taste of many drugs. This chapter was focused on its general introduction, traditional uses, and pharmacological activities. This could help in further studies on Glycyrrhiza glabra for exploring its potential in preventing and treating diseases and other commercial uses. Different studies have confirmed that the Glycyrrhiza glabra derived compound glycyrrhizin and its derivatives have antiviral activities. The most common serious side-effects reported following chronic use of high dose of licorice root are hypokalemia and hypertension. Its role has been identified in many clinical conditions, such as anti-inflammatory, anti-ulcer, antiviral, antimicrobial, antioxidants, antiatherogenic, anticarcinogenic, antimutagenic, antitussive expectorant, and hepatoprotective, etc.
