ABSTRACT

During the physical stage, the incident radiation ionizes and excites the molecules of the medium, creating secondary electrons. The resulting species are unstable and undergo fast rearrangement in the physicochemical stage. Radiation chemistry is of great importance in understanding radiation biology. Modeling approaches have been very successful in simulating the detailed chemical reactions induced by different types of ionizing radiations, notably those involved in chemical dosimeters. Regarding the simulation methods in radiation chemistry, the results obtained by SBS and IRT are slightly different. This difference was noted previously in model systems comprising one or two types of particles, notably those comprising charged particles. On the contrary, classical reaction kinetics are based on uniform concentrations of particles and imply closed systems. This is more similar to biological systems, in which the radiolytic species are generated in small compartments such as cellular organelles.