ABSTRACT
This chapter reviews the concepts and principles relevant to investigating the effectiveness of nanoceria for tissue engineering applications in the critical literature review. Nanoparticle-based therapies may be the answer as they have been utilized to deliver therapeutic agents to a diseased site and promote the accumulation of therapeutic levels of drugs at the target site. Cerium oxide nanoparticles have extensive potential as therapeutic agents in Reactive oxygen species–mediated diseases, anti-cancer, and anti-inflammatory applications. Ceria nanoparticles potentially have superior properties compared to conventionally used antioxidants. Nanoparticles of different kinds have been extensively studied as cancer treatment agents or drug-carrying molecules due to their unique physiological, optical, and magnetic properties to increase the efficacy of treatment and to reduce the side effects of the treatment. The catalytically active sites of nanoceria are known to be oxygen defects at the surface of the particles and/or delocalized electron density at the surface of the nanoparticles.
