ABSTRACT

The engineering and fabrication of nanomachines and nanorobots is an emerging and fascinating field of the advanced nanotechnology. Both nanomachines and nanorobots are with overall dimension below or at the micrometer range; however, they are made of assemblies constructed by individual nanoscale components. A light-activated switch to turn DNA nanomachine on and off is developed in response to UV and visible light. The design of a nanorobot requires an autonomy swimming and navigation strategy for overcoming the low Reynolds number viscous drag and Brownian motion. Synthetic nanomachines might be integrated with motile microorganism to build hybrid, biologically powered nanorobots. The nanorobotics bacteria are capable of navigating through the bloodstream and thus targeting the tumor cells throughout the body. The combination of nanomotor with electromechanical actuators and an incorporated biosensor element is a novel platform for inventing the next generation of advanced nanomachines and nanorobotics.