ABSTRACT

Hypertension affects 10% of pregnancies and is associated with significant maternal and fetal morbidity and mortality. While primary hyperaldosteronism is a common cause of secondary hypertension, the case literature is limited in pregnancy. Diagnosis of primary hyperaldosteronism in pregnancy is challenging due to complex physiological changes that occur in the renin-angiotensin-aldosterone axis. Currently, there are no clear guidelines for management of primary hyperaldosteronism during pregnancy. Medical management with use of antihypertensive medications that are safe in pregnancy is key to preventing fetal and maternal complications. Surgery can be considered in the second trimester in those with uncontrolled hypertension.