ABSTRACT

Acromegaly is a rare disease that is caused by excessive growth hormone production. Diagnosis of acromegaly during pregnancy is often confounded by pregnancy-associated hormonal changes. Therefore, diagnosis is typically deferred until the postpartum setting. There is a tendency toward clinical improvement of acromegaly during pregnancy due to the contribution of pregnancy-associated growth hormone resistance. Thus, patients with preexisting acromegaly prior to pregnancy are often able to have medical therapy discontinued during pregnancy. If clinical signs of pituitary tumor growth occur, medical or surgical management may be considered.