ABSTRACT
Many cancer treatments, especially those involving alkylating agents, bone marrow transplant (BMT), or pelvic radiation, can damage reproductive function — Early referral for fertility preservation prior to treatment is necessary. Menstrual disorders such as heavy bleeding and amenorrhea are common during cancer treatment. Adolescents undergoing cancer treatment should not be assumed to be abstinent; sexual health counseling and contraception if needed should be provided. About 75% of pediatric cancer survivors will experience at least on late effect — Endocrine dysfunction, infertility, breast cancer, ovarian cancer, sexual dysfunction. Cancer treatment may have an immediate or delayed effect on reproductive function, and the gynecologist must be prepared to manage puberty induction, hormone replacement therapy, and fertility preservation along with sexual dysfunction and chronic vulvovaginal disease. A multidisciplinary approach to cancer treatment and survival is encouraged.
