ABSTRACT
This chapter discusses the existing data and reports on scientific studies illustrating the metabolic properties of coffee constituents along with their biological significance and chemical activity. Studies following those methodologies and case studies reported for a conclusion of coffee consumption with cardiovascular and metabolic risks. Literature surveys and conclusions drawn from such studies represented the experimental and meta-analysis data showing the positive effects of coffee consumption toward a beneficial and neutralizing potential of coffee metabolites. Studies focusing on both the beneficial and risky effects of coffee consumption provided data enough adequate to support their investigations. Endothelial dysfunction is a severe attribute to metabolic syndrome and atherosclerosis. The intake of caffeine has been connected with a high number of biological effects, mainly concerning the stimulation of the central and sympathetic nervous systems, typically associated with a feeling of alertness after coffee consumption.
