ABSTRACT

This chapter focuses on current advances in targeted nanoparticle-based magnetic theranostics. The use of magnetic fields for remote control of magnetic nanoparticles (MNPs) effects within the body and the ability to visualize these particles by magnetic resonance imaging and computed tomography create the basis for theranostics. Side effects and low efficiency of anticancer drugs demand the need for the development of treatment technologies based on novel principles. Active targeting of magnetic nanoparticles involves functionalization of the surface with ligands capable of specific binding to the site of interest. Diagnostics with the help of functionalized MNPs in vitro is very important, since it allow determining the functional state of the body according to the level of specific metabolites and hormones.