ABSTRACT
Nano drug delivery system deals with the enhancement of bioavailability of orally administered therapeutic agents, target-specific drug delivery, and prolonged half-life of parenteral. Thymoquinone (TQ) is the chief active ingredient of Nigella sativa and has been incorporated in innumerable nano-formulations to assess its diverse pharmacological activity against many human illnesses including cancer, hypertension (HTN), diabetes, allergies, eczema, and immunogenic disorders. The major problem in developing TQ based nanoformulation is its highly hydrophobic nature which limits its solubility and its bioavailability. However, the emergence of surface engineering of the nanoparticle carrier systems has fixed this problem for TQ and hence, several nanoformulations have been developed and evaluated. This chapter briefly discusses the health applications of TQ based nanoformulations prepared through different techniques.
