ABSTRACT
Ursolic acid (UA) is the most promising member of the triterpenoid groups, is a naturally derived pentacyclic triterpenoid. The basic structure is composed of ursane, lupane, and oleanane, which is leading to different pharmacological activities of UA. Though having numerous physiological properties like anti-inflammatory, anticancerous, bone regeneration, anti-fungal, hepatoprotective, antioxidant, it possesses one major drawback is less solubility in water, followed by poor bioavailability in the drug delivery system. Another drawback of UA is the off-target drug delivery system which results in less use in the medical world. Having these major side-effects, the use of UA is not restricted and overcome with the help of nanotechnology, by developing different formulations like liposomes, nanoemulsions, micelles, solid lipid nanoparticles (SLNs), and nanostructured lipid carriers (NLCs), etc.
